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November 2022

Progesterone Antisense Oligonucleotides Inhibits Breast Cancer Growth

Progesterone Antisense Oligonucleotides Inhibits Breast Cancer Growth

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Progesterone Antisense Oligonucleotides Inhibits Breast Cancer Growth   Hormone status of breast cancer Breast cancer arises from the growth of an abnormal mass of cells across the breast tissues. When this tumor is examined, it may be sensitive to some female hormones like estrogen and progesterone. The cells in breast tumors have receptors for these […]

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Antisense Oligonucleotide Therapy in Oncology

Antisense Oligonucleotide Therapy in Oncology

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Antisense Oligonucleotide Therapy in Oncology   Summary Antisense oligonucleotide therapy plays a vital role in cancer and genetic disorders. This therapy involves the use of oligonucleotides that are complementary to specific target DNA or RNA in the nucleus. Oligonucleotides bind the complementary sequence and inhibit the synthesis of specific proteins by different mechanisms. Thus, downregulating

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A Breakthrough in Cancer Treatment: How Successful is Antisense Oligonucleotides (ASOs)

A Breakthrough in Cancer Treatment: How Successful is Antisense Oligonucleotides (ASOs)

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A Breakthrough in Cancer Treatment: How Successful is Antisense Oligonucleotides (ASOs)   Oligonucleotides Small sequences of nucleic acids, either DNA or RNA that have many important applications in genetic research are called oligonucleotides.   Antisense oligonucleotides (ASOs) These are designed in the laboratory having a specific sequence complementary to our sequence of interest. They bind

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Chemotherapy With Antisense Oligonucleotide Therapy Improves Disease-Free Survival

Chemotherapy With Antisense Oligonucleotide Therapy Improves Disease-Free Survival

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Chemotherapy With Antisense Oligonucleotide Therapy Improves Disease-Free Survival   Chemotherapy Chemotherapy is a cancer treatment that involves the use of medication to eradicate cancer cells. Chemotherapy drugs come in a wide variety of forms, but they all function similarly. They block cancer cells from procreating, which stops them from developing and spreading throughout the body.

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Poly (ADP-ribose) polymerase

Poly (ADP-ribose) polymerase and its role in cancer in combination with 2-deoxyglucose (2DG)

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PARP is a family containing many proteins that have important functions in the cell like the stability of the genome, repair of damaged DNA, and apoptosis or programmed cell death.   PARP family members There are 17 proteins in this family. PARP 1 was the first protein from this family that was studied in detail.

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