MDM2 expression

Chemosensitization by Antisense Oligonucleotides Targeting MDM2 Expression   MDM2 gene MDM2 oncogene in humans encodes Mouse double minute 2 homolog or MDM2 protein. This protein negatively regulates a tumor-suppressive gene in the cell called P53. It also acts as an E3-Ubiquitin ligase protein that binds the N-terminal of the p53 protein and inhibits the transcriptional […]