AOHC Breast Cancer Chemotherapy Dosage Calculator<\/title>\r\n<style>\r\n :root{\r\n --aohc-navy:#0B2240;\r\n --aohc-navy2:#0D2B5A;\r\n --aohc-aqua:#00B7C7;\r\n --aohc-aqua2:#20C2CF;\r\n --aohc-white:#fff;\r\n --aohc-gray:#E9EEF4;\r\n --aohc-graphite:#1F2A37;\r\n --aohc-shadow:0 10px 36px rgba(11,34,64,.12);\r\n --aohc-gap:18px;\r\n --aohc-highlight:#e6fcff;\r\n --aohc-highlight-border:#20c2cf;\r\n --aohc-radius:14px;\r\n }\r\n\r\n *,*::before,*::after{box-sizing:border-box}\r\n\r\n html,body{\r\n margin:0;\r\n padding:0;\r\n background:var(--aohc-gray);\r\n color:var(--aohc-graphite);\r\n font-family:\"Inter\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",Roboto,Arial,sans-serif;\r\n line-height:1.5;\r\n -webkit-text-size-adjust:100%;\r\n }\r\n\r\n img{max-width:100%;height:auto}\r\n\r\n .wrap-1121{max-width:1200px;margin:0 auto;padding:0 16px 64px}\r\n\r\n \/* ---------- Hero ---------- *\/\r\n .hero-1121{\r\n background:var(--aohc-navy);\r\n color:var(--aohc-white);\r\n padding:28px 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.drug-content{display:none}\r\n .drug-content.active{display:block}\r\n\r\n \/* ---------- Results ---------- *\/\r\n .result-1121{display:grid;gap:0;font-size:1.05em}\r\n .line-1121{\r\n display:flex;\r\n justify-content:space-between;\r\n gap:14px;\r\n border-bottom:1.1px dashed var(--aohc-gray);\r\n padding:9px 0;\r\n }\r\n .value-1121{font-weight:800;color:var(--aohc-navy2);text-align:right}\r\n\r\n \/* ---------- Disclaimer ---------- *\/\r\n .disclaimer-1121{\r\n background:linear-gradient(90deg,#fff9e1 0,#ffe9e1 100%);\r\n color:#aa1e2c;\r\n border-left:5px solid #e6612f;\r\n padding:12px 15px;\r\n border-radius:8px;\r\n margin-top:12px;\r\n font-size:.98em;\r\n }\r\n\r\n \/* ---------- Tables ---------- *\/\r\n .table-wrap{width:100%;overflow-x:auto;-webkit-overflow-scrolling:touch}\r\n .table-1121{\r\n width:100%;\r\n border-collapse:separate;\r\n border-spacing:0;\r\n margin:14px 0 7px;\r\n border:1.2px solid var(--aohc-gray);\r\n border-radius:9px;\r\n overflow:hidden;\r\n box-shadow:0 4px 16px rgba(11,34,64,.04);\r\n }\r\n .table-1121 th,.table-1121 td{\r\n padding:10px 9px;\r\n border-bottom:1px solid var(--aohc-gray);\r\n text-align:left;\r\n vertical-align:top;\r\n }\r\n .table-1121 thead th{background:var(--aohc-navy2);color:var(--aohc-white);font-size:.9em}\r\n .table-1121 tbody tr:nth-child(even){background:var(--aohc-gray)}\r\n .table-1121 td[id]{font-weight:800;color:var(--aohc-navy2);white-space:nowrap}\r\n\r\n .carboplatin-section{\r\n background:var(--aohc-highlight);\r\n border:1px solid var(--aohc-highlight-border);\r\n border-radius:10px;\r\n padding:15px;\r\n margin:10px 0;\r\n }\r\n\r\n .note-block{font-size:.93em;color:var(--aohc-navy2);margin:6px 0 18px}\r\n\r\n ul{padding-left:20px}\r\n ul li{margin:6px 0}\r\n\r\n \/* ============ RESPONSIVE ============ *\/\r\n @media (min-width:640px){\r\n .field-grid{grid-template-columns:1fr 1fr}\r\n .field-grid .full{grid-column:1 \/ -1}\r\n }\r\n\r\n @media (max-width:768px){\r\n .hero-1121{padding:22px 16px 20px;margin-bottom:14px}\r\n .card-1121{padding:16px 14px 14px}\r\n h2{font-size:1.12rem}\r\n }\r\n\r\n @media (max-width:560px){\r\n .wrap-1121{padding:0 10px 48px}\r\n .hero-1121{border-radius:0 0 12px 12px}\r\n .seg-1121{display:flex;width:100%}\r\n .seg-1121 button{flex:1}\r\n .drug-tab{flex:1 1 calc(50% - 8px)}\r\n .btn-1121{flex:1 1 100%}\r\n \/* Make wide tables scroll horizontally instead of overflowing the screen *\/\r\n .table-1121{font-size:.9em}\r\n .table-1121 th,.table-1121 td{padding:8px 7px}\r\n }\r\n<\/style>\r\n<\/head>\r\n<body>\r\n<div class=\"wrap-1121\">\r\n\r\n <header class=\"hero-1121\">\r\n <h1>AOHC Breast Cancer Chemotherapy Dosage Calculator<\/h1>\r\n <div class=\"sub\">Comprehensive calculator for all major breast cancer chemotherapy drugs. BSA-based calculations with dose reduction options (100%, 75%, 50%, 20%) and precise carboplatin dosing using the Calvert formula.<\/div>\r\n <div class=\"meta-1121\">\r\n <span class=\"chip-1121\">AOHC Tools<\/span>\r\n <span class=\"chip-1121\">Updated: 30 Aug 2025<\/span>\r\n <span class=\"chip-1121\">BSA + Calvert Formula<\/span>\r\n <\/div>\r\n <\/header>\r\n\r\n <div class=\"callout-1121\">\r\n <strong>Important:<\/strong> All dosing calculations are for educational purposes only. Always verify with current protocols and consult with the oncology team before administration. Dose modifications may be needed based on toxicity, organ function, and patient factors.\r\n <\/div>\r\n\r\n <div class=\"grid-1121\">\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>Patient Information<\/h2>\r\n <div class=\"field-grid\">\r\n <div>\r\n <label for=\"weight\">Weight<\/label>\r\n <input id=\"weight\" min=\"0\" step=\"0.1\" type=\"number\" inputmode=\"decimal\" placeholder=\"e.g., 70\" \/>\r\n <div class=\"help-1121\">Body weight (kg).<\/div>\r\n <\/div>\r\n <div>\r\n <label for=\"height\">Height<\/label>\r\n <input id=\"height\" min=\"0\" step=\"0.1\" type=\"number\" inputmode=\"decimal\" placeholder=\"e.g., 170\" \/>\r\n <div class=\"help-1121\">Height (cm).<\/div>\r\n <\/div>\r\n <div>\r\n <label for=\"age\">Age<\/label>\r\n <input id=\"age\" max=\"120\" min=\"0\" step=\"1\" type=\"number\" inputmode=\"numeric\" placeholder=\"e.g., 55\" \/>\r\n <div class=\"help-1121\">Age (years) \u2014 for carboplatin dosing.<\/div>\r\n <\/div>\r\n <div>\r\n <label>Gender<\/label>\r\n <div class=\"seg-1121\" role=\"tablist\" aria-label=\"Gender\">\r\n <button id=\"genderFemale\" type=\"button\" role=\"tab\" aria-pressed=\"true\">Female<\/button>\r\n <button id=\"genderMale\" type=\"button\" role=\"tab\" aria-pressed=\"false\">Male<\/button>\r\n <\/div>\r\n <div class=\"help-1121\">For creatinine clearance calculation.<\/div>\r\n <\/div>\r\n <div>\r\n <label for=\"creatinine\">Serum Creatinine<\/label>\r\n <input id=\"creatinine\" min=\"0\" step=\"0.1\" type=\"number\" inputmode=\"decimal\" placeholder=\"e.g., 1.0\" \/>\r\n <div class=\"help-1121\">mg\/dL \u2014 for carboplatin dosing.<\/div>\r\n <\/div>\r\n <div>\r\n <label for=\"doseReduction\">Dose Reduction<\/label>\r\n <select id=\"doseReduction\">\r\n <option value=\"100\">100% (Standard)<\/option>\r\n <option value=\"75\">75% Reduction<\/option>\r\n <option value=\"50\">50% Reduction<\/option>\r\n <option value=\"20\">20% Reduction (Low-dose)<\/option>\r\n <\/select>\r\n <div class=\"help-1121\">Applied to BSA-based drugs.<\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n <div class=\"btn-row\">\r\n <button id=\"calcBtn\" type=\"button\" class=\"btn-1121\">Calculate All Drugs<\/button>\r\n <button id=\"resetBtn\" type=\"button\" class=\"btn-1121 secondary\">Reset<\/button>\r\n <\/div>\r\n <div id=\"notice\" class=\"notice-1121\"><\/div>\r\n <\/section>\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>BSA & Renal Function Results<\/h2>\r\n <div class=\"result-1121\">\r\n <div class=\"line-1121\"><span>Body Surface Area (BSA)<\/span><span class=\"value-1121\" id=\"bsa-result\">\u2014<\/span><\/div>\r\n <div class=\"line-1121\"><span>Creatinine Clearance (CrCl)<\/span><span class=\"value-1121\" id=\"crcl-result\">\u2014<\/span><\/div>\r\n <div class=\"line-1121\"><span>Dose Reduction Applied<\/span><span class=\"value-1121\" id=\"reduction-result\">\u2014<\/span><\/div>\r\n <div class=\"line-1121\"><span>Patient Weight<\/span><span class=\"value-1121\" id=\"weight-result\">\u2014<\/span><\/div>\r\n <div class=\"line-1121\"><span>Patient Age<\/span><span class=\"value-1121\" id=\"age-result\">\u2014<\/span><\/div>\r\n <\/div>\r\n <div class=\"note-block\">\r\n BSA via the Mosteller formula. CrCl via the Cockcroft-Gault formula. Carboplatin dosing uses the Calvert formula: Dose = AUC × (CrCl + 25).\r\n <\/div>\r\n <\/section>\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>Drug Dosages<\/h2>\r\n\r\n <div class=\"drug-tabs\" role=\"tablist\">\r\n <button class=\"drug-tab active\" data-target=\"tab-anthra\" type=\"button\">Anthracyclines<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-taxanes\" type=\"button\">Taxanes<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-alkyl\" type=\"button\">Alkylating Agents<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-anti\" type=\"button\">Antimetabolites<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-platinum\" type=\"button\">Platinum Compounds<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-other\" type=\"button\">Other Agents<\/button>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content active\" id=\"tab-anthra\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Doxorubicin<\/strong><\/td><td>60-75 mg\/m\u00b2<\/td><td id=\"doxorubicin-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Epirubicin<\/strong><\/td><td>75-90 mg\/m\u00b2<\/td><td id=\"epirubicin-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Liposomal Doxorubicin<\/strong><\/td><td>50 mg\/m\u00b2<\/td><td id=\"lipodox-dose\">\u2014<\/td><td>IV every 28 days<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Maximum cumulative dose for doxorubicin: 550 mg\/m\u00b2. Monitor cardiac function (ECHO\/MUGA).<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-taxanes\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Paclitaxel<\/strong><\/td><td>175 mg\/m\u00b2<\/td><td id=\"paclitaxel-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Paclitaxel Weekly<\/strong><\/td><td>80 mg\/m\u00b2<\/td><td id=\"paclitaxel-weekly-dose\">\u2014<\/td><td>IV weekly<\/td><\/tr>\r\n <tr><td><strong>Docetaxel<\/strong><\/td><td>75-100 mg\/m\u00b2<\/td><td id=\"docetaxel-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Docetaxel Weekly<\/strong><\/td><td>35 mg\/m\u00b2<\/td><td id=\"docetaxel-weekly-dose\">\u2014<\/td><td>IV weekly<\/td><\/tr>\r\n <tr><td><strong>Abraxane (nab-Paclitaxel)<\/strong><\/td><td>260 mg\/m\u00b2<\/td><td id=\"abraxane-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Abraxane Weekly<\/strong><\/td><td>125 mg\/m\u00b2<\/td><td id=\"abraxane-weekly-dose\">\u2014<\/td><td>IV weekly x3, q4w<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Premedicate for hypersensitivity reactions. Monitor for peripheral neuropathy.<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-alkyl\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Cyclophosphamide<\/strong><\/td><td>600 mg\/m\u00b2<\/td><td id=\"cyclophosphamide-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Cyclophosphamide (oral)<\/strong><\/td><td>100 mg\/m\u00b2<\/td><td id=\"cyclo-oral-dose\">\u2014<\/td><td>PO daily x14 days<\/td><\/tr>\r\n <tr><td><strong>Ifosfamide<\/strong><\/td><td>1200 mg\/m\u00b2<\/td><td id=\"ifosfamide-dose\">\u2014<\/td><td>IV daily x5 days<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Ensure adequate hydration. Monitor for hemorrhagic cystitis with cyclophosphamide\/ifosfamide.<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-anti\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>5-Fluorouracil<\/strong><\/td><td>600 mg\/m\u00b2<\/td><td id=\"fluorouracil-dose\">\u2014<\/td><td>IV days 1,8 q28d<\/td><\/tr>\r\n <tr><td><strong>Capecitabine<\/strong><\/td><td>1250 mg\/m\u00b2<\/td><td id=\"capecitabine-dose\">\u2014<\/td><td>PO BID x14d q21d<\/td><\/tr>\r\n <tr><td><strong>Methotrexate<\/strong><\/td><td>40 mg\/m\u00b2<\/td><td id=\"methotrexate-dose\">\u2014<\/td><td>IV days 1,8 q28d<\/td><\/tr>\r\n <tr><td><strong>Gemcitabine<\/strong><\/td><td>1000 mg\/m\u00b2<\/td><td id=\"gemcitabine-dose\">\u2014<\/td><td>IV days 1,8 q21d<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Monitor for mucositis, hand-foot syndrome (capecitabine). Leucovorin rescue may be needed with high-dose MTX.<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-platinum\">\r\n <div class=\"carboplatin-section\">\r\n <h3 style=\"margin-top:0\">Carboplatin Dosing (Calvert Formula)<\/h3>\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Target AUC<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><th>Clinical Use<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>AUC 6<\/strong><\/td><td id=\"carboplatin-auc6-dose\">\u2014<\/td><td>IV every 21 days<\/td><td>Standard adjuvant<\/td><\/tr>\r\n <tr><td><strong>AUC 5<\/strong><\/td><td id=\"carboplatin-auc5-dose\">\u2014<\/td><td>IV every 21 days<\/td><td>Combination therapy<\/td><\/tr>\r\n <tr><td><strong>AUC 4<\/strong><\/td><td id=\"carboplatin-auc4-dose\">\u2014<\/td><td>IV every 21 days<\/td><td>Elderly\/reduced function<\/td><\/tr>\r\n <tr><td><strong>AUC 2<\/strong><\/td><td id=\"carboplatin-auc2-dose\">\u2014<\/td><td>IV weekly<\/td><td>Weekly schedule<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Calvert Formula:<\/strong> Dose (mg) = Target AUC \u00d7 (CrCl + 25). CrCl capped at 150 mL\/min for safety. (Carboplatin uses AUC targets rather than the BSA dose-reduction %.)<\/div>\r\n <\/div>\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Cisplatin<\/strong><\/td><td>75 mg\/m\u00b2<\/td><td id=\"cisplatin-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Monitor renal function, hearing, and neuropathy. Adequate hydration essential for cisplatin.<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-other\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Vinorelbine<\/strong><\/td><td>25 mg\/m\u00b2<\/td><td id=\"vinorelbine-dose\">\u2014<\/td><td>IV weekly<\/td><\/tr>\r\n <tr><td><strong>Eribulin<\/strong><\/td><td>1.4 mg\/m\u00b2<\/td><td id=\"eribulin-dose\">\u2014<\/td><td>IV days 1,8 q21d<\/td><\/tr>\r\n <tr><td><strong>Ixabepilone<\/strong><\/td><td>40 mg\/m\u00b2<\/td><td id=\"ixabepilone-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Mitomycin<\/strong><\/td><td>10 mg\/m\u00b2<\/td><td id=\"mitomycin-dose\">\u2014<\/td><td>IV every 42 days<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Monitor for specific toxicities. Eribulin: QT prolongation. Vinorelbine: severe constipation.<\/div>\r\n <\/div>\r\n <\/section>\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>Safety Information<\/h2>\r\n <div class=\"disclaimer-1121\">\r\n <strong>This calculator is for educational purposes only.<\/strong> It does <em>not<\/em> provide treatment recommendations.\r\n <\/div>\r\n <ul>\r\n <li><strong>Always verify dosing<\/strong> with current institutional protocols and drug monographs.<\/li>\r\n <li><strong>Carboplatin dosing:<\/strong> Requires accurate creatinine clearance. Consider capping CrCl at 150 mL\/min.<\/li>\r\n <li><strong>Dose modifications<\/strong> may be required based on organ function, performance status, toxicity, and prior treatments.<\/li>\r\n <li><strong>Maximum doses<\/strong> and cumulative dose limits must be observed (e.g., doxorubicin 550 mg\/m\u00b2).<\/li>\r\n <\/ul>\r\n <p><strong>Never administer chemotherapy without oncologist supervision and appropriate monitoring.<\/strong><\/p>\r\n <\/section>\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>References<\/h2>\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug Class<\/th><th>Key References<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td>Carboplatin (Calvert Formula)<\/td><td>Calvert et al. J Clin Oncol 1989; BC Cancer protocols<\/td><\/tr>\r\n <tr><td>Anthracyclines<\/td><td>FDA prescribing information, BC Cancer Drug Manual<\/td><\/tr>\r\n <tr><td>Taxanes<\/td><td>NCCN Guidelines, European Medicines Agency<\/td><\/tr>\r\n <tr><td>Other Agents<\/td><td>Susan G. Komen Foundation, Clinical studies<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <\/section>\r\n\r\n <\/div>\r\n<\/div>\r\n\r\n<script>\r\n(function(){\r\n \/\/ ---- Gender segmented control ----\r\n var genderFemale = document.getElementById('genderFemale');\r\n var genderMale = document.getElementById('genderMale');\r\n var isFemale = true;\r\n function setGender(female){\r\n isFemale = female;\r\n genderFemale.setAttribute('aria-pressed', female ? 'true' : 'false');\r\n genderMale.setAttribute('aria-pressed', female ? 'false' : 'true');\r\n }\r\n genderFemale.addEventListener('click', function(){ setGender(true); });\r\n genderMale.addEventListener('click', function(){ setGender(false); });\r\n\r\n \/\/ ---- Drug class tabs ----\r\n var tabs = document.querySelectorAll('.drug-tab');\r\n tabs.forEach(function(tab){\r\n tab.addEventListener('click', function(){\r\n tabs.forEach(function(t){ t.classList.remove('active'); });\r\n document.querySelectorAll('.drug-content').forEach(function(c){ c.classList.remove('active'); });\r\n tab.classList.add('active');\r\n document.getElementById(tab.dataset.target).classList.add('active');\r\n });\r\n });\r\n\r\n \/\/ ---- BSA-based drugs: [min] or [min, max] of mg\/m\u00b2 ----\r\n var drugs = {\r\n 'doxorubicin-dose':[60,75], 'epirubicin-dose':[75,90], 'lipodox-dose':[50],\r\n 'paclitaxel-dose':[175], 'paclitaxel-weekly-dose':[80], 'docetaxel-dose':[75,100],\r\n 'docetaxel-weekly-dose':[35], 'abraxane-dose':[260], 'abraxane-weekly-dose':[125],\r\n 'cyclophosphamide-dose':[600], 'cyclo-oral-dose':[100], 'ifosfamide-dose':[1200],\r\n 'fluorouracil-dose':[600], 'capecitabine-dose':[1250], 'methotrexate-dose':[40],\r\n 'gemcitabine-dose':[1000], 'cisplatin-dose':[75], 'vinorelbine-dose':[25],\r\n 'eribulin-dose':[1.4], 'ixabepilone-dose':[40], 'mitomycin-dose':[10]\r\n };\r\n var carboAuc = {\r\n 'carboplatin-auc6-dose':6, 'carboplatin-auc5-dose':5,\r\n 'carboplatin-auc4-dose':4, 'carboplatin-auc2-dose':2\r\n };\r\n\r\n function fmtMg(mg){\r\n return (mg < 10) ? (Math.round(mg*10)\/10) : Math.round(mg);\r\n }\r\n\r\n var notice = document.getElementById('notice');\r\n function showNotice(msg){ notice.textContent = msg; notice.classList.add('show'); }\r\n function hideNotice(){ notice.classList.remove('show'); }\r\n\r\n function setAll(text){\r\n Object.keys(drugs).forEach(function(id){\r\n var el = document.getElementById(id); if(el) el.textContent = text;\r\n });\r\n Object.keys(carboAuc).forEach(function(id){\r\n var el = document.getElementById(id); if(el) el.textContent = text;\r\n });\r\n }\r\n\r\n \/\/ ---- Calculate ----\r\n document.getElementById('calcBtn').addEventListener('click', function(){\r\n hideNotice();\r\n var weight = parseFloat(document.getElementById('weight').value);\r\n var height = parseFloat(document.getElementById('height').value);\r\n var age = parseFloat(document.getElementById('age').value);\r\n var scr = parseFloat(document.getElementById('creatinine').value);\r\n var reduction = parseFloat(document.getElementById('doseReduction').value);\r\n var r = reduction \/ 100;\r\n\r\n if(!(weight > 0) || !(height > 0)){\r\n showNotice('Please enter a valid weight (kg) and height (cm) to calculate BSA-based doses.');\r\n return;\r\n }\r\n\r\n \/\/ BSA \u2014 Mosteller\r\n var bsa = Math.sqrt((height * weight) \/ 3600);\r\n\r\n \/\/ CrCl \u2014 Cockcroft-Gault (needs age + creatinine)\r\n var crcl = null;\r\n if(age > 0 && scr > 0){\r\n crcl = ((140 - age) * weight * (isFemale ? 0.85 : 1)) \/ (72 * scr);\r\n if(crcl < 0) crcl = 0;\r\n }\r\n\r\n \/\/ BSA-based doses\r\n Object.keys(drugs).forEach(function(id){\r\n var el = document.getElementById(id);\r\n if(!el) return;\r\n var vals = drugs[id].map(function(v){ return fmtMg(v * bsa * r); });\r\n el.textContent = (vals.length === 2) ? (vals[0] + '\u2013' + vals[1] + ' mg') : (vals[0] + ' mg');\r\n });\r\n\r\n \/\/ Carboplatin \u2014 Calvert (CrCl capped at 150)\r\n Object.keys(carboAuc).forEach(function(id){\r\n var el = document.getElementById(id);\r\n if(!el) return;\r\n if(crcl === null){\r\n el.textContent = 'Enter age + creatinine';\r\n } else {\r\n var crclCapped = Math.min(crcl, 150);\r\n el.textContent = Math.round(carboAuc[id] * (crclCapped + 25)) + ' mg';\r\n }\r\n });\r\n\r\n \/\/ Results panel\r\n document.getElementById('bsa-result').textContent = bsa.toFixed(2) + ' m\u00b2';\r\n document.getElementById('crcl-result').textContent = (crcl === null) ? 'Enter age + creatinine' : (Math.round(crcl) + ' mL\/min');\r\n document.getElementById('reduction-result').textContent = reduction + '%';\r\n document.getElementById('weight-result').textContent = weight + ' kg';\r\n document.getElementById('age-result').textContent = (age > 0) ? (age + ' years') : '\u2014';\r\n });\r\n\r\n \/\/ ---- Reset ----\r\n document.getElementById('resetBtn').addEventListener('click', function(){\r\n ['weight','height','age','creatinine'].forEach(function(id){ document.getElementById(id).value = ''; });\r\n document.getElementById('doseReduction').value = '100';\r\n setGender(true);\r\n setAll('\u2014');\r\n ['bsa-result','crcl-result','reduction-result','weight-result','age-result'].forEach(function(id){\r\n document.getElementById(id).textContent = '\u2014';\r\n });\r\n hideNotice();\r\n });\r\n})();\r\n<\/script>\r\n<\/body>\r\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>AOHC Breast Cancer Chemotherapy Dosage Calculator AOHC Breast Cancer Chemotherapy Dosage Calculator Comprehensive calculator for all major breast cancer chemotherapy drugs. BSA-based calculations with dose reduction options (100%, 75%, 50%, 20%) and precise carboplatin dosing using the Calvert formula. AOHC Tools Updated: 30 Aug 2025 BSA + Calvert Formula Important: All dosing calculations are for … <a title=\"AOHC Breast Cancer Chemotherapy Dosage Calculator\" class=\"read-more\" href=\"https:\/\/artofhealingcancer.com\/blogs\/aohc-breast-cancer-chemotherapy-dosage-calculator\/\" aria-label=\"Read more about AOHC Breast Cancer Chemotherapy Dosage Calculator\">Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[222],"tags":[],"class_list":["post-572","post","type-post","status-publish","format-standard","hentry","category-dosing-calculator"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t<meta name=\"description\" content=\"AOHC Breast Cancer Chemotherapy Dosage Calculator AOHC Breast Cancer Chemotherapy Dosage Calculator Comprehensive calculator for all major breast cancer chemotherapy drugs. 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BSA-based calculations with dose reduction options (100%, 75%, 50%, 20%) and precise carboplatin dosing using the Calvert formula. AOHC Tools Updated: 30 Aug 2025 BSA + Calvert Formula Important: All dosing calculations are for","og:url":"https:\/\/artofhealingcancer.com\/blogs\/aohc-breast-cancer-chemotherapy-dosage-calculator\/","og:image":"https:\/\/artofhealingcancer.com\/wp-content\/uploads\/2022\/07\/Art-of-Healing-Cancer-Logo-Final-with-tagline.svg","og:image:secure_url":"https:\/\/artofhealingcancer.com\/wp-content\/uploads\/2022\/07\/Art-of-Healing-Cancer-Logo-Final-with-tagline.svg","article:published_time":"2025-08-29T18:43:11+00:00","article:modified_time":"2026-06-17T09:02:26+00:00","twitter:card":"summary_large_image","twitter:title":"AOHC Breast Cancer Chemotherapy Dosage Calculator - Art of Healing Cancer","twitter:description":"AOHC Breast Cancer Chemotherapy Dosage Calculator AOHC Breast Cancer Chemotherapy Dosage Calculator Comprehensive calculator for all major breast cancer chemotherapy drugs. BSA-based calculations with dose reduction options (100%, 75%, 50%, 20%) and precise carboplatin dosing using the Calvert formula. AOHC Tools Updated: 30 Aug 2025 BSA + Calvert Formula Important: All dosing calculations are for","twitter:image":"https:\/\/artofhealingcancer.com\/wp-content\/uploads\/2022\/07\/Art-of-Healing-Cancer-Logo-Final-with-tagline.svg"},"aioseo_meta_data":{"post_id":"572","title":null,"description":null,"keywords":null,"keyphrases":{"focus":{"keyphrase":"","score":0,"analysis":{"keyphraseInTitle":{"score":0,"maxScore":9,"error":1}}},"additional":[]},"primary_term":null,"canonical_url":null,"og_title":null,"og_description":null,"og_object_type":"default","og_image_type":"default","og_image_url":null,"og_image_width":null,"og_image_height":null,"og_image_custom_url":null,"og_image_custom_fields":null,"og_video":"","og_custom_url":null,"og_article_section":null,"og_article_tags":null,"twitter_use_og":false,"twitter_card":"default","twitter_image_type":"default","twitter_image_url":null,"twitter_image_custom_url":null,"twitter_image_custom_fields":null,"twitter_title":null,"twitter_description":null,"schema":{"blockGraphs":[],"customGraphs":[],"default":{"data":{"Article":[],"Course":[],"Dataset":[],"FAQPage":[],"Movie":[],"Person":[],"Product":[],"ProductReview":[],"Car":[],"Recipe":[],"Service":[],"SoftwareApplication":[],"WebPage":[]},"graphName":"BlogPosting","isEnabled":true},"graphs":[]},"schema_type":"default","schema_type_options":null,"pillar_content":false,"robots_default":true,"robots_noindex":false,"robots_noarchive":false,"robots_nosnippet":false,"robots_nofollow":false,"robots_noimageindex":false,"robots_noodp":false,"robots_notranslate":false,"robots_max_snippet":"-1","robots_max_videopreview":"-1","robots_max_imagepreview":"large","priority":null,"frequency":"default","local_seo":null,"breadcrumb_settings":null,"limit_modified_date":false,"ai":{"faqs":[],"keyPoints":[],"schemas":[],"titles":[],"descriptions":[],"socialPosts":{"email":[],"linkedin":[],"twitter":[],"facebook":[],"instagram":[]}},"created":"2025-08-29 18:43:11","updated":"2026-06-17 09:18:30","seo_analyzer_scan_date":null},"aioseo_breadcrumb":"<div class=\"aioseo-breadcrumbs\"><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/artofhealingcancer.com\/blogs\" title=\"Home\">Home<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">»<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\t<a href=\"https:\/\/artofhealingcancer.com\/blogs\/category\/dosing-calculator\/\" title=\"Dosing Calculator\">Dosing Calculator<\/a>\n\t\t<\/span><span class=\"aioseo-breadcrumb-separator\">»<\/span><span class=\"aioseo-breadcrumb\">\n\t\t\tAOHC Breast Cancer Chemotherapy Dosage Calculator\n\t\t<\/span><\/div>","aioseo_breadcrumb_json":[{"label":"Home","link":"https:\/\/artofhealingcancer.com\/blogs"},{"label":"Dosing Calculator","link":"https:\/\/artofhealingcancer.com\/blogs\/category\/dosing-calculator\/"},{"label":"AOHC Breast Cancer Chemotherapy Dosage Calculator","link":"https:\/\/artofhealingcancer.com\/blogs\/aohc-breast-cancer-chemotherapy-dosage-calculator\/"}],"_links":{"self":[{"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/posts\/572","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/comments?post=572"}],"version-history":[{"count":16,"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/posts\/572\/revisions"}],"predecessor-version":[{"id":647,"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/posts\/572\/revisions\/647"}],"wp:attachment":[{"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/media?parent=572"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/categories?post=572"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/artofhealingcancer.com\/blogs\/wp-json\/wp\/v2\/tags?post=572"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

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\n\t\t\t\t\t\r\n\r\n\r\n\r\n\r\nAOHC Breast Cancer Chemotherapy Dosage Calculator<\/title>\r\n<style>\r\n :root{\r\n --aohc-navy:#0B2240;\r\n --aohc-navy2:#0D2B5A;\r\n --aohc-aqua:#00B7C7;\r\n --aohc-aqua2:#20C2CF;\r\n --aohc-white:#fff;\r\n --aohc-gray:#E9EEF4;\r\n --aohc-graphite:#1F2A37;\r\n --aohc-shadow:0 10px 36px rgba(11,34,64,.12);\r\n --aohc-gap:18px;\r\n --aohc-highlight:#e6fcff;\r\n --aohc-highlight-border:#20c2cf;\r\n --aohc-radius:14px;\r\n }\r\n\r\n *,*::before,*::after{box-sizing:border-box}\r\n\r\n html,body{\r\n margin:0;\r\n padding:0;\r\n background:var(--aohc-gray);\r\n color:var(--aohc-graphite);\r\n font-family:\"Inter\",-apple-system,BlinkMacSystemFont,\"Segoe UI\",Roboto,Arial,sans-serif;\r\n line-height:1.5;\r\n -webkit-text-size-adjust:100%;\r\n }\r\n\r\n img{max-width:100%;height:auto}\r\n\r\n .wrap-1121{max-width:1200px;margin:0 auto;padding:0 16px 64px}\r\n\r\n \/* ---------- Hero ---------- *\/\r\n .hero-1121{\r\n background:var(--aohc-navy);\r\n 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.drug-content{display:none}\r\n .drug-content.active{display:block}\r\n\r\n \/* ---------- Results ---------- *\/\r\n .result-1121{display:grid;gap:0;font-size:1.05em}\r\n .line-1121{\r\n display:flex;\r\n justify-content:space-between;\r\n gap:14px;\r\n border-bottom:1.1px dashed var(--aohc-gray);\r\n padding:9px 0;\r\n }\r\n .value-1121{font-weight:800;color:var(--aohc-navy2);text-align:right}\r\n\r\n \/* ---------- Disclaimer ---------- *\/\r\n .disclaimer-1121{\r\n background:linear-gradient(90deg,#fff9e1 0,#ffe9e1 100%);\r\n color:#aa1e2c;\r\n border-left:5px solid #e6612f;\r\n padding:12px 15px;\r\n border-radius:8px;\r\n margin-top:12px;\r\n font-size:.98em;\r\n }\r\n\r\n \/* ---------- Tables ---------- *\/\r\n .table-wrap{width:100%;overflow-x:auto;-webkit-overflow-scrolling:touch}\r\n .table-1121{\r\n width:100%;\r\n border-collapse:separate;\r\n border-spacing:0;\r\n margin:14px 0 7px;\r\n border:1.2px solid var(--aohc-gray);\r\n border-radius:9px;\r\n overflow:hidden;\r\n box-shadow:0 4px 16px rgba(11,34,64,.04);\r\n }\r\n .table-1121 th,.table-1121 td{\r\n padding:10px 9px;\r\n border-bottom:1px solid var(--aohc-gray);\r\n text-align:left;\r\n vertical-align:top;\r\n }\r\n .table-1121 thead th{background:var(--aohc-navy2);color:var(--aohc-white);font-size:.9em}\r\n .table-1121 tbody tr:nth-child(even){background:var(--aohc-gray)}\r\n .table-1121 td[id]{font-weight:800;color:var(--aohc-navy2);white-space:nowrap}\r\n\r\n .carboplatin-section{\r\n background:var(--aohc-highlight);\r\n border:1px solid var(--aohc-highlight-border);\r\n border-radius:10px;\r\n padding:15px;\r\n margin:10px 0;\r\n }\r\n\r\n .note-block{font-size:.93em;color:var(--aohc-navy2);margin:6px 0 18px}\r\n\r\n ul{padding-left:20px}\r\n ul li{margin:6px 0}\r\n\r\n \/* ============ RESPONSIVE ============ *\/\r\n @media (min-width:640px){\r\n .field-grid{grid-template-columns:1fr 1fr}\r\n .field-grid .full{grid-column:1 \/ -1}\r\n }\r\n\r\n @media (max-width:768px){\r\n .hero-1121{padding:22px 16px 20px;margin-bottom:14px}\r\n .card-1121{padding:16px 14px 14px}\r\n h2{font-size:1.12rem}\r\n }\r\n\r\n @media (max-width:560px){\r\n .wrap-1121{padding:0 10px 48px}\r\n .hero-1121{border-radius:0 0 12px 12px}\r\n .seg-1121{display:flex;width:100%}\r\n .seg-1121 button{flex:1}\r\n .drug-tab{flex:1 1 calc(50% - 8px)}\r\n .btn-1121{flex:1 1 100%}\r\n \/* Make wide tables scroll horizontally instead of overflowing the screen *\/\r\n .table-1121{font-size:.9em}\r\n .table-1121 th,.table-1121 td{padding:8px 7px}\r\n }\r\n<\/style>\r\n<\/head>\r\n<body>\r\n<div class=\"wrap-1121\">\r\n\r\n <header class=\"hero-1121\">\r\n <h1>AOHC Breast Cancer Chemotherapy Dosage Calculator<\/h1>\r\n <div class=\"sub\">Comprehensive calculator for all major breast cancer chemotherapy drugs. BSA-based calculations with dose reduction options (100%, 75%, 50%, 20%) and precise carboplatin dosing using the Calvert formula.<\/div>\r\n <div class=\"meta-1121\">\r\n <span class=\"chip-1121\">AOHC Tools<\/span>\r\n <span class=\"chip-1121\">Updated: 30 Aug 2025<\/span>\r\n <span class=\"chip-1121\">BSA + Calvert Formula<\/span>\r\n <\/div>\r\n <\/header>\r\n\r\n <div class=\"callout-1121\">\r\n <strong>Important:<\/strong> All dosing calculations are for educational purposes only. Always verify with current protocols and consult with the oncology team before administration. Dose modifications may be needed based on toxicity, organ function, and patient factors.\r\n <\/div>\r\n\r\n <div class=\"grid-1121\">\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>Patient Information<\/h2>\r\n <div class=\"field-grid\">\r\n <div>\r\n <label for=\"weight\">Weight<\/label>\r\n <input id=\"weight\" min=\"0\" step=\"0.1\" type=\"number\" inputmode=\"decimal\" placeholder=\"e.g., 70\" \/>\r\n <div class=\"help-1121\">Body weight (kg).<\/div>\r\n <\/div>\r\n <div>\r\n <label for=\"height\">Height<\/label>\r\n <input id=\"height\" min=\"0\" step=\"0.1\" type=\"number\" inputmode=\"decimal\" placeholder=\"e.g., 170\" \/>\r\n <div class=\"help-1121\">Height (cm).<\/div>\r\n <\/div>\r\n <div>\r\n <label for=\"age\">Age<\/label>\r\n <input id=\"age\" max=\"120\" min=\"0\" step=\"1\" type=\"number\" inputmode=\"numeric\" placeholder=\"e.g., 55\" \/>\r\n <div class=\"help-1121\">Age (years) \u2014 for carboplatin dosing.<\/div>\r\n <\/div>\r\n <div>\r\n <label>Gender<\/label>\r\n <div class=\"seg-1121\" role=\"tablist\" aria-label=\"Gender\">\r\n <button id=\"genderFemale\" type=\"button\" role=\"tab\" aria-pressed=\"true\">Female<\/button>\r\n <button id=\"genderMale\" type=\"button\" role=\"tab\" aria-pressed=\"false\">Male<\/button>\r\n <\/div>\r\n <div class=\"help-1121\">For creatinine clearance calculation.<\/div>\r\n <\/div>\r\n <div>\r\n <label for=\"creatinine\">Serum Creatinine<\/label>\r\n <input id=\"creatinine\" min=\"0\" step=\"0.1\" type=\"number\" inputmode=\"decimal\" placeholder=\"e.g., 1.0\" \/>\r\n <div class=\"help-1121\">mg\/dL \u2014 for carboplatin dosing.<\/div>\r\n <\/div>\r\n <div>\r\n <label for=\"doseReduction\">Dose Reduction<\/label>\r\n <select id=\"doseReduction\">\r\n <option value=\"100\">100% (Standard)<\/option>\r\n <option value=\"75\">75% Reduction<\/option>\r\n <option value=\"50\">50% Reduction<\/option>\r\n <option value=\"20\">20% Reduction (Low-dose)<\/option>\r\n <\/select>\r\n <div class=\"help-1121\">Applied to BSA-based drugs.<\/div>\r\n <\/div>\r\n <\/div>\r\n\r\n <div class=\"btn-row\">\r\n <button id=\"calcBtn\" type=\"button\" class=\"btn-1121\">Calculate All Drugs<\/button>\r\n <button id=\"resetBtn\" type=\"button\" class=\"btn-1121 secondary\">Reset<\/button>\r\n <\/div>\r\n <div id=\"notice\" class=\"notice-1121\"><\/div>\r\n <\/section>\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>BSA & Renal Function Results<\/h2>\r\n <div class=\"result-1121\">\r\n <div class=\"line-1121\"><span>Body Surface Area (BSA)<\/span><span class=\"value-1121\" id=\"bsa-result\">\u2014<\/span><\/div>\r\n <div class=\"line-1121\"><span>Creatinine Clearance (CrCl)<\/span><span class=\"value-1121\" id=\"crcl-result\">\u2014<\/span><\/div>\r\n <div class=\"line-1121\"><span>Dose Reduction Applied<\/span><span class=\"value-1121\" id=\"reduction-result\">\u2014<\/span><\/div>\r\n <div class=\"line-1121\"><span>Patient Weight<\/span><span class=\"value-1121\" id=\"weight-result\">\u2014<\/span><\/div>\r\n <div class=\"line-1121\"><span>Patient Age<\/span><span class=\"value-1121\" id=\"age-result\">\u2014<\/span><\/div>\r\n <\/div>\r\n <div class=\"note-block\">\r\n BSA via the Mosteller formula. CrCl via the Cockcroft-Gault formula. Carboplatin dosing uses the Calvert formula: Dose = AUC × (CrCl + 25).\r\n <\/div>\r\n <\/section>\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>Drug Dosages<\/h2>\r\n\r\n <div class=\"drug-tabs\" role=\"tablist\">\r\n <button class=\"drug-tab active\" data-target=\"tab-anthra\" type=\"button\">Anthracyclines<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-taxanes\" type=\"button\">Taxanes<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-alkyl\" type=\"button\">Alkylating Agents<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-anti\" type=\"button\">Antimetabolites<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-platinum\" type=\"button\">Platinum Compounds<\/button>\r\n <button class=\"drug-tab\" data-target=\"tab-other\" type=\"button\">Other Agents<\/button>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content active\" id=\"tab-anthra\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Doxorubicin<\/strong><\/td><td>60-75 mg\/m\u00b2<\/td><td id=\"doxorubicin-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Epirubicin<\/strong><\/td><td>75-90 mg\/m\u00b2<\/td><td id=\"epirubicin-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Liposomal Doxorubicin<\/strong><\/td><td>50 mg\/m\u00b2<\/td><td id=\"lipodox-dose\">\u2014<\/td><td>IV every 28 days<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Maximum cumulative dose for doxorubicin: 550 mg\/m\u00b2. Monitor cardiac function (ECHO\/MUGA).<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-taxanes\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Paclitaxel<\/strong><\/td><td>175 mg\/m\u00b2<\/td><td id=\"paclitaxel-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Paclitaxel Weekly<\/strong><\/td><td>80 mg\/m\u00b2<\/td><td id=\"paclitaxel-weekly-dose\">\u2014<\/td><td>IV weekly<\/td><\/tr>\r\n <tr><td><strong>Docetaxel<\/strong><\/td><td>75-100 mg\/m\u00b2<\/td><td id=\"docetaxel-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Docetaxel Weekly<\/strong><\/td><td>35 mg\/m\u00b2<\/td><td id=\"docetaxel-weekly-dose\">\u2014<\/td><td>IV weekly<\/td><\/tr>\r\n <tr><td><strong>Abraxane (nab-Paclitaxel)<\/strong><\/td><td>260 mg\/m\u00b2<\/td><td id=\"abraxane-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Abraxane Weekly<\/strong><\/td><td>125 mg\/m\u00b2<\/td><td id=\"abraxane-weekly-dose\">\u2014<\/td><td>IV weekly x3, q4w<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Premedicate for hypersensitivity reactions. Monitor for peripheral neuropathy.<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-alkyl\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Cyclophosphamide<\/strong><\/td><td>600 mg\/m\u00b2<\/td><td id=\"cyclophosphamide-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Cyclophosphamide (oral)<\/strong><\/td><td>100 mg\/m\u00b2<\/td><td id=\"cyclo-oral-dose\">\u2014<\/td><td>PO daily x14 days<\/td><\/tr>\r\n <tr><td><strong>Ifosfamide<\/strong><\/td><td>1200 mg\/m\u00b2<\/td><td id=\"ifosfamide-dose\">\u2014<\/td><td>IV daily x5 days<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Ensure adequate hydration. Monitor for hemorrhagic cystitis with cyclophosphamide\/ifosfamide.<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-anti\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>5-Fluorouracil<\/strong><\/td><td>600 mg\/m\u00b2<\/td><td id=\"fluorouracil-dose\">\u2014<\/td><td>IV days 1,8 q28d<\/td><\/tr>\r\n <tr><td><strong>Capecitabine<\/strong><\/td><td>1250 mg\/m\u00b2<\/td><td id=\"capecitabine-dose\">\u2014<\/td><td>PO BID x14d q21d<\/td><\/tr>\r\n <tr><td><strong>Methotrexate<\/strong><\/td><td>40 mg\/m\u00b2<\/td><td id=\"methotrexate-dose\">\u2014<\/td><td>IV days 1,8 q28d<\/td><\/tr>\r\n <tr><td><strong>Gemcitabine<\/strong><\/td><td>1000 mg\/m\u00b2<\/td><td id=\"gemcitabine-dose\">\u2014<\/td><td>IV days 1,8 q21d<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Monitor for mucositis, hand-foot syndrome (capecitabine). Leucovorin rescue may be needed with high-dose MTX.<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-platinum\">\r\n <div class=\"carboplatin-section\">\r\n <h3 style=\"margin-top:0\">Carboplatin Dosing (Calvert Formula)<\/h3>\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Target AUC<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><th>Clinical Use<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>AUC 6<\/strong><\/td><td id=\"carboplatin-auc6-dose\">\u2014<\/td><td>IV every 21 days<\/td><td>Standard adjuvant<\/td><\/tr>\r\n <tr><td><strong>AUC 5<\/strong><\/td><td id=\"carboplatin-auc5-dose\">\u2014<\/td><td>IV every 21 days<\/td><td>Combination therapy<\/td><\/tr>\r\n <tr><td><strong>AUC 4<\/strong><\/td><td id=\"carboplatin-auc4-dose\">\u2014<\/td><td>IV every 21 days<\/td><td>Elderly\/reduced function<\/td><\/tr>\r\n <tr><td><strong>AUC 2<\/strong><\/td><td id=\"carboplatin-auc2-dose\">\u2014<\/td><td>IV weekly<\/td><td>Weekly schedule<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Calvert Formula:<\/strong> Dose (mg) = Target AUC \u00d7 (CrCl + 25). CrCl capped at 150 mL\/min for safety. (Carboplatin uses AUC targets rather than the BSA dose-reduction %.)<\/div>\r\n <\/div>\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Cisplatin<\/strong><\/td><td>75 mg\/m\u00b2<\/td><td id=\"cisplatin-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Monitor renal function, hearing, and neuropathy. Adequate hydration essential for cisplatin.<\/div>\r\n <\/div>\r\n\r\n \r\n <div class=\"drug-content\" id=\"tab-other\">\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug<\/th><th>Standard Dose<\/th><th>Calculated Dose<\/th><th>Schedule<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td><strong>Vinorelbine<\/strong><\/td><td>25 mg\/m\u00b2<\/td><td id=\"vinorelbine-dose\">\u2014<\/td><td>IV weekly<\/td><\/tr>\r\n <tr><td><strong>Eribulin<\/strong><\/td><td>1.4 mg\/m\u00b2<\/td><td id=\"eribulin-dose\">\u2014<\/td><td>IV days 1,8 q21d<\/td><\/tr>\r\n <tr><td><strong>Ixabepilone<\/strong><\/td><td>40 mg\/m\u00b2<\/td><td id=\"ixabepilone-dose\">\u2014<\/td><td>IV every 21 days<\/td><\/tr>\r\n <tr><td><strong>Mitomycin<\/strong><\/td><td>10 mg\/m\u00b2<\/td><td id=\"mitomycin-dose\">\u2014<\/td><td>IV every 42 days<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <div class=\"note-block\"><strong>Note:<\/strong> Monitor for specific toxicities. Eribulin: QT prolongation. Vinorelbine: severe constipation.<\/div>\r\n <\/div>\r\n <\/section>\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>Safety Information<\/h2>\r\n <div class=\"disclaimer-1121\">\r\n <strong>This calculator is for educational purposes only.<\/strong> It does <em>not<\/em> provide treatment recommendations.\r\n <\/div>\r\n <ul>\r\n <li><strong>Always verify dosing<\/strong> with current institutional protocols and drug monographs.<\/li>\r\n <li><strong>Carboplatin dosing:<\/strong> Requires accurate creatinine clearance. Consider capping CrCl at 150 mL\/min.<\/li>\r\n <li><strong>Dose modifications<\/strong> may be required based on organ function, performance status, toxicity, and prior treatments.<\/li>\r\n <li><strong>Maximum doses<\/strong> and cumulative dose limits must be observed (e.g., doxorubicin 550 mg\/m\u00b2).<\/li>\r\n <\/ul>\r\n <p><strong>Never administer chemotherapy without oncologist supervision and appropriate monitoring.<\/strong><\/p>\r\n <\/section>\r\n\r\n \r\n <section class=\"card-1121\">\r\n <h2>References<\/h2>\r\n <div class=\"table-wrap\">\r\n <table class=\"table-1121\">\r\n <thead><tr><th>Drug Class<\/th><th>Key References<\/th><\/tr><\/thead>\r\n <tbody>\r\n <tr><td>Carboplatin (Calvert Formula)<\/td><td>Calvert et al. J Clin Oncol 1989; BC Cancer protocols<\/td><\/tr>\r\n <tr><td>Anthracyclines<\/td><td>FDA prescribing information, BC Cancer Drug Manual<\/td><\/tr>\r\n <tr><td>Taxanes<\/td><td>NCCN Guidelines, European Medicines Agency<\/td><\/tr>\r\n <tr><td>Other Agents<\/td><td>Susan G. Komen Foundation, Clinical studies<\/td><\/tr>\r\n <\/tbody>\r\n <\/table>\r\n <\/div>\r\n <\/section>\r\n\r\n <\/div>\r\n<\/div>\r\n\r\n<script>\r\n(function(){\r\n \/\/ ---- Gender segmented control ----\r\n var genderFemale = document.getElementById('genderFemale');\r\n var genderMale = document.getElementById('genderMale');\r\n var isFemale = true;\r\n function setGender(female){\r\n isFemale = female;\r\n genderFemale.setAttribute('aria-pressed', female ? 'true' : 'false');\r\n genderMale.setAttribute('aria-pressed', female ? 'false' : 'true');\r\n }\r\n genderFemale.addEventListener('click', function(){ setGender(true); });\r\n genderMale.addEventListener('click', function(){ setGender(false); });\r\n\r\n \/\/ ---- Drug class tabs ----\r\n var tabs = document.querySelectorAll('.drug-tab');\r\n tabs.forEach(function(tab){\r\n tab.addEventListener('click', function(){\r\n tabs.forEach(function(t){ t.classList.remove('active'); });\r\n document.querySelectorAll('.drug-content').forEach(function(c){ c.classList.remove('active'); });\r\n tab.classList.add('active');\r\n document.getElementById(tab.dataset.target).classList.add('active');\r\n });\r\n });\r\n\r\n \/\/ ---- BSA-based drugs: [min] or [min, max] of mg\/m\u00b2 ----\r\n var drugs = {\r\n 'doxorubicin-dose':[60,75], 'epirubicin-dose':[75,90], 'lipodox-dose':[50],\r\n 'paclitaxel-dose':[175], 'paclitaxel-weekly-dose':[80], 'docetaxel-dose':[75,100],\r\n 'docetaxel-weekly-dose':[35], 'abraxane-dose':[260], 'abraxane-weekly-dose':[125],\r\n 'cyclophosphamide-dose':[600], 'cyclo-oral-dose':[100], 'ifosfamide-dose':[1200],\r\n 'fluorouracil-dose':[600], 'capecitabine-dose':[1250], 'methotrexate-dose':[40],\r\n 'gemcitabine-dose':[1000], 'cisplatin-dose':[75], 'vinorelbine-dose':[25],\r\n 'eribulin-dose':[1.4], 'ixabepilone-dose':[40], 'mitomycin-dose':[10]\r\n };\r\n var carboAuc = {\r\n 'carboplatin-auc6-dose':6, 'carboplatin-auc5-dose':5,\r\n 'carboplatin-auc4-dose':4, 'carboplatin-auc2-dose':2\r\n };\r\n\r\n function fmtMg(mg){\r\n return (mg < 10) ? (Math.round(mg*10)\/10) : Math.round(mg);\r\n }\r\n\r\n var notice = document.getElementById('notice');\r\n function showNotice(msg){ notice.textContent = msg; notice.classList.add('show'); }\r\n function hideNotice(){ notice.classList.remove('show'); }\r\n\r\n function setAll(text){\r\n Object.keys(drugs).forEach(function(id){\r\n var el = document.getElementById(id); if(el) el.textContent = text;\r\n });\r\n Object.keys(carboAuc).forEach(function(id){\r\n var el = document.getElementById(id); if(el) el.textContent = text;\r\n });\r\n }\r\n\r\n \/\/ ---- Calculate ----\r\n document.getElementById('calcBtn').addEventListener('click', function(){\r\n hideNotice();\r\n var weight = parseFloat(document.getElementById('weight').value);\r\n var height = parseFloat(document.getElementById('height').value);\r\n var age = parseFloat(document.getElementById('age').value);\r\n var scr = parseFloat(document.getElementById('creatinine').value);\r\n var reduction = parseFloat(document.getElementById('doseReduction').value);\r\n var r = reduction \/ 100;\r\n\r\n if(!(weight > 0) || !(height > 0)){\r\n showNotice('Please enter a valid weight (kg) and height (cm) to calculate BSA-based doses.');\r\n return;\r\n }\r\n\r\n \/\/ BSA \u2014 Mosteller\r\n var bsa = Math.sqrt((height * weight) \/ 3600);\r\n\r\n \/\/ CrCl \u2014 Cockcroft-Gault (needs age + creatinine)\r\n var crcl = null;\r\n if(age > 0 && scr > 0){\r\n crcl = ((140 - age) * weight * (isFemale ? 0.85 : 1)) \/ (72 * scr);\r\n if(crcl < 0) crcl = 0;\r\n }\r\n\r\n \/\/ BSA-based doses\r\n Object.keys(drugs).forEach(function(id){\r\n var el = document.getElementById(id);\r\n if(!el) return;\r\n var vals = drugs[id].map(function(v){ return fmtMg(v * bsa * r); });\r\n el.textContent = (vals.length === 2) ? (vals[0] + '\u2013' + vals[1] + ' mg') : (vals[0] + ' mg');\r\n });\r\n\r\n \/\/ Carboplatin \u2014 Calvert (CrCl capped at 150)\r\n Object.keys(carboAuc).forEach(function(id){\r\n var el = document.getElementById(id);\r\n if(!el) return;\r\n if(crcl === null){\r\n el.textContent = 'Enter age + creatinine';\r\n } else {\r\n var crclCapped = Math.min(crcl, 150);\r\n el.textContent = Math.round(carboAuc[id] * (crclCapped + 25)) + ' mg';\r\n }\r\n });\r\n\r\n \/\/ Results panel\r\n document.getElementById('bsa-result').textContent = bsa.toFixed(2) + ' m\u00b2';\r\n document.getElementById('crcl-result').textContent = (crcl === null) ? 'Enter age + creatinine' : (Math.round(crcl) + ' mL\/min');\r\n document.getElementById('reduction-result').textContent = reduction + '%';\r\n document.getElementById('weight-result').textContent = weight + ' kg';\r\n document.getElementById('age-result').textContent = (age > 0) ? (age + ' years') : '\u2014';\r\n });\r\n\r\n \/\/ ---- Reset ----\r\n document.getElementById('resetBtn').addEventListener('click', function(){\r\n ['weight','height','age','creatinine'].forEach(function(id){ document.getElementById(id).value = ''; });\r\n document.getElementById('doseReduction').value = '100';\r\n setGender(true);\r\n setAll('\u2014');\r\n ['bsa-result','crcl-result','reduction-result','weight-result','age-result'].forEach(function(id){\r\n document.getElementById(id).textContent = '\u2014';\r\n });\r\n hideNotice();\r\n });\r\n})();\r\n<\/script>\r\n<\/body>\r\n<\/html>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>AOHC Breast Cancer Chemotherapy Dosage Calculator AOHC Breast Cancer Chemotherapy Dosage Calculator Comprehensive calculator for all major breast cancer chemotherapy drugs. BSA-based calculations with dose reduction options (100%, 75%, 50%, 20%) and precise carboplatin dosing using the Calvert formula. AOHC Tools Updated: 30 Aug 2025 BSA + Calvert Formula Important: All dosing calculations are for … <a title=\"AOHC Breast Cancer Chemotherapy Dosage Calculator\" class=\"read-more\" href=\"https:\/\/artofhealingcancer.com\/blogs\/aohc-breast-cancer-chemotherapy-dosage-calculator\/\" aria-label=\"Read more about AOHC Breast Cancer Chemotherapy Dosage Calculator\">Read more<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[222],"tags":[],"class_list":["post-572","post","type-post","status-publish","format-standard","hentry","category-dosing-calculator"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t<meta name=\"description\" content=\"AOHC Breast Cancer Chemotherapy Dosage Calculator AOHC Breast Cancer Chemotherapy Dosage Calculator Comprehensive calculator for all major breast cancer chemotherapy drugs. 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